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It means the highest amount or greatest degree of something. The most what it means: Can most be used in place of almost?: How to use most in a sentence. “the most” is used when comparing. Modules. auth. login. initiatelogin When you invest in most-missouris 529 education plan (the plan), you are purchasing portfolio units issued by the program trust. We offer field trips for any type of group 7 days a week, so plan a fun day at the most with interactive science activities and … The meaning of most is greatest in quantity, extent, or degree.